Fluconazole prophylaxis in high-risk, very low birth weight infants
نویسندگان
چکیده
منابع مشابه
Targeted short-term fluconazole prophylaxis among very low birth weight and extremely low birth weight infants.
OBJECTIVES To assess whether targeted short-term fluconazole prophylaxis reduces late-onset (>3 days of age) invasive fungal infection (IFI) among very low birth weight infants and extremely low birth weight (ELBW) infants and to assess mortality rates, toxicity, and costs associated with this intervention. METHODS An observational study of 2 subsequent epochs of inborn infants with birth wei...
متن کاملFluconazole prophylaxis against fungal colonization and invasive fungal infection in very low birth weight infants.
BACKGROUND Fungal infections are common cause of morbidity and mortality in very low birth weight Infants OBJECTIVES To evaluate the efficacy of prophylactic Fluconazole in preventing fungal colonization and invasive fungal infection in VLBW infants. DESIGN Prospective, randomized, double blind placebo controlled clinical trial. SETTING Tertiary level Neonatal intensive care unit. SUBJE...
متن کاملFosfluconazole for Antifungal Prophylaxis in Very Low Birth Weight Infants
We conducted a retrospective case series study to evaluate the safety of fosfluconazole prophylaxis for preventing invasive fungal infection in VLBW infants with a central vascular access. Fosfluconazole was administered intravenously at a dose of 6 mg/kg everyday during which time a central venous catheter was placed. A total of 23 infants met the criteria for enrollment in our study. No cases...
متن کاملEfficacy of Fluconazole Prophylaxis on Invasive Candidiasis Infection in Extremely Low Birth Weight Neonates
Background: Invasive candidiasis infection is one of the main life-threatening problems for extremely low birth weight (ELBW) neonates who are in the neonatal intensive care unit (NICU). Candidiasis can cause mortality, short-term morbidity, and long-term neurodevelopmental outcome in infected infants who survive. Therefore, since several years ago fluconazole prophylaxis has begun for prematur...
متن کاملAssessing mortality risk in very low birth weight infants.
INTRODUCTION Preterm birth is the most important univariant risk factor of neonatal mortality. Assessment of risk factors affecting mortality in preterm infants with very low birth weight is important for the treatment of this highly vulnerable population. OBJECTIVE Detection of risk factors for neonatal mortality in very low birth weight premature infants. METHODS The current study was con...
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ژورنال
عنوان ژورنال: Korean Journal of Pediatrics
سال: 2007
ISSN: 1738-1061
DOI: 10.3345/kjp.2007.50.7.636